At the end of March, we covered Behance's major site redesign, at which point we learned that the startup was launching over 20K new projects every week, with 1 million projects created to date, and its network had doubled over the last month, with 10 million visits to its network in the last 30 days. Since its founding in 2006 and launch less than a year later, Behance, which, for those unfamiliar, is an online platform on which creative professionals can connect, showcase and discover creative work, has been a bootstrapped enterprise, Behance CEO Scott Belsky tells us. But, no longer. Today, the startup is announcing that it has raised its first round of outside funding, a $6.5 million round, led by Union Square Ventures, with noted investors like Amazon CEO Jeff Bezos (via Bezos Expeditions, his personal investment fund), Path Founder Dave Morin, Yves Behar, Chris Dixon, Dave Tisch, Dave McClure, Alexis Ohanian, and Garrett Camp.
Okay, okay, it's here -- but when can you actually get your hands on Samsung's Galaxy S III? Well, if you're in Europe, you're looking at a May 29th release for the HSPA+ version. Those of us in North America, Japan and Korea will have to wait a bit longer for speed -- the LTE version of the handset will be hitting those areas in the summer. Specifically, it'll be arriving in the US in June. In all, the phone will be hitting some 296 mobile operators in 145 countries, according to the company.
Director X opens up about the singer's new video, premiering tonight on MTV at 7:50 p.m.! By Jocelyn Vena
Justin Bieber in his video for "Boyfriend" Photo: Island/Def Jam
Justin Bieber will show off an even swaggier side of himself tonight when he premieres his "Boyfriend" video on MTV. Before the premiere, Bieber gave fans a sneak peek of the sunny party clip.
The teaser features Bieber snuggling with a very pretty young lady, surrounded by muscle cars and his pals. It was that straightforward concept that intrigued the pop star and his team.
"It was just cars and the simplicity that they liked. Cars, girls, just young people hanging out, having fun, that kind of thing. When I heard it, I thought that's what it should be," Director X, who helmed the clip, told MTV News. "From what they wanted to do with Justin and the song and who he is and his age now, I thought that was it. They should expect the Justin they know, just a little more grown-up."
While he had never worked with the singer before, he admits that, like everyone else in the world, he was fully aware of who Bieber is. "I've seen him. I mean, he's Justin Bieber. There's no way you don't know who the kid is, but I've never worked with him before or met him before. So my exposure to him is the way any other TV watcher, Internet watcher would know him," he said, adding that he left the April video shoot a fan. "He's a good kid. He comes to work, gets the job done, dedicated to the gig. I mean, I like him."
Want more behind-the-scenes scoop from Bieber himself? The singer will sit down with MTV News' Sway Calloway tonight to premiere his "Boyfriend" music video during "MTV First: Justin Bieber" live at 7:50 p.m. ET on MTV. After the video premieres on air, Bieber will chat with Sway for 30 minutes on MTV.com, opening up about the clip as well as his June 19 album release, Believe. But that's not all: If you have a burning question for Bieber, you can get in on the fun by commenting below or tweeting @MTVNews with the hashtag #MTVFirst or #AskBieber.
Immediately following the premiere, the "Boyfriend" video will be available on MTV.com, so Beliebers can watch it over and over and over again.
Don't miss the "Boyfriend" video premiere tonight at 7:50 p.m. ET/PT on MTV during "MTV First: Justin Bieber," followed by a live Q&A with Justin himself on MTV.com!
After all the rumors, leaks and hype, we finally get to lay eyes on the Samsung Galaxy S III -- the unicorn of the Android world. It's impressive to say the least, big, beautiful, and built with natural curves to set it apart from the pack. We're even digging the fact that it isn't just your basic black. It's safe to say Samsung has went all out to bring us the best they have to offer.
There's a lot of new technology packed in there as well. Natural Interactions recognize your voice, and your face, and new motion gestures make it something new and different. We love new and different.
Regarding U.S. availability, Samsung's official statement:
Samsung Mobile is planning a U.S. version of Galaxy S III, optimized for the fastest LTE and HSPA+ networks in the U.S., which will be available in the summer of 2012. Exact timing and retail channel availability is not being announced at this time. We believe the Galaxy S III is the most anticipated product in the 20-year history of Samsung Mobile; therefore, we will continue to share information as it becomes available.
1 May 2012Last updated at 03:54 ETBy Michelle RobertsHealth editor, BBC News website
Dr James Flanagan, who led the research, says a pre-test for breast cancer could save lives
A genetic test could help predict breast cancer many years before the disease is diagnosed, experts hope.
Ultimately the findings, in the journal Cancer Research, could lead to a simple blood test to screen women, they say.
The test looks for how genes are altered by environmental factors like alcohol and hormones - a process known as epigenetics.
One in five women is thought to have such a genetic "switch" that doubles breast cancer risk.
Continue reading the main story
?Start Quote
By piecing together how this happens, we can look at ways of preventing the disease and detecting it earlier to give people the best possible chance of survival?
End QuoteBaroness Delyth MorganBreast Cancer Campaign
The scientists from Imperial College London analysed blood samples from 1,380 women of various ages, 640 of whom went on to develop breast cancer.
And they found a strong link between breast cancer risk and molecular modification of a single gene called ATM, which is found on white blood cells.
Predicting cancer
They then looked for evidence of what was causing this change. Specifically, they looked for a chemical effect called methylation, which is known to act as a "gene switch".
Women showing the highest methylation levels affecting the ATM gene were twice as likely to develop breast cancer compared with those with the lowest levels.
In some cases the changes were evident up to 11 years before a breast tumour was diagnosed.
Dr James Flanagan, of Imperial College London, who led the new research, said: "We know that genetic variation contributes to a person's risk of disease.
"With this new study we can now also say that epigenetic variation, or differences in how genes are modified, also has a role.
"We hope that this research is just the beginning of our understanding about the epigenetic component of breast cancer risk and in the coming years we hope to find many more examples of genes that contribute to a person's risk.
"The challenge will be how to incorporate all of this new information into the computer models that are currently used for individual risk prediction."
It is not yet clear why breast cancer risk might be linked to changes in a white blood cell gene.
Continue reading the main story
Epigenetics
The focus is on targeting cancer-causing errors in the way the body reads DNA code, rather than errors in the genetic code itself
A series of chemical switches determine whether genes are turned on or off, and ultimately what the cell will look like and how it will function
Alterations in this "epigenetic" control can lead to cancer
Environmental factors like hormones can act as triggers for these errors
Scientists are working on new drugs that can regulate gene expression and effectively solve epigenetic problems
But the team envisage that a blood test could be used in combination with other information about breast cancer risk, such as family history and the presence of other known breast cancer genes, to help identify those women at greatest risk of developing the disease in the future.
These women could then be closely monitored and offered pre-emptive treatment, such as surgery.
Baroness Delyth Morgan of the Breast Cancer Campaign, which funded the work, said: "By piecing together how this happens, we can look at ways of preventing the disease and detecting it earlier to give people the best possible chance of survival."
Laura Bell of Cancer Research UK said: "This study gives us a fascinating glimpse of the future and the promise that the emerging field of epigenetics holds. But it's too early to say exactly how these particular changes might affect our ability to detect who is likely to develop certain types of cancer.
"With further studies, scientists will increase our knowledge of how genetic switches like this interplay together to affect breast cancer risk, with the hope that one day this could lead to a blood test that could help predict a woman's chance of getting the disease."
You may remember a certain, somewhat anticipated cloud service finally coming in to land in recent days. That wasn't the only news in nebular computing last week, however: perhaps in anticipation of Google's long-rumored Drive service, Microsoft made some updates to the Windows Phone app for its own offering, SkyDrive. This comes not long after the release of desktop SkyDrive applications for Windows and OSX, all suggesting that Redmond's hoping to cut itself as large a slice of the cloud-storage pie as it can, preferably while others are still taking their seats at the table. We spent some time with the latest quiver of tools from Microsoft, to see how they've progressed.
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Nationwide Poll found 7 out of 10 women suffering from menopausal symptoms are not treated; Majority not talking to their doctors about various relief options
May 1, 2012 (Chevy Chase, MD) Women going through menopause now have a first-of-its-kind interactive guide to help them better understand their menu of treatment options, including whether hormone therapy may be right for them. The Endocrine Society and its Hormone Health Network today released the "Menopause Map," an online tool to help women and their doctors discuss which hormonal and non-hormonal treatment options would be most effective and safe to relieve the sometimes debilitating symptoms of menopause. A new accompanying survey found that the majority of women facing challenging symptoms are concerned about hormone treatment and are not discussing it, or other non-hormonal options, with their doctor. The Map was developed by Endocrine Society physician experts who specialize in menopause management.
The tool is based on the latest unbiased research and is intended to jumpstart conversations between women and their doctors about the choices available to them as they approach and experience menopause.
Hormone therapy has been under intense scrutiny since 2002, when a large government study called the Women's Health Initiative (WHI) reported that hormone therapyspecifically the combination of estrogen and progestin togetherincreased the risk for blood clots, stroke, breast cancer and heart attacks. The researchers halted the study and concluded that the risks of hormone therapy outweighed the benefits. Although the study was designed to evaluate the role of hormone therapy in the prevention of diseases related to aging, many women and their doctors also abandoned it as therapy for menopausal symptoms.
Over the past 10 years, additional research has found that the level of risk depends on the individual woman, her health history, age, and the number of years since her menopause began. In general, younger women (under 60) who have recently started menopause are at a lower risk than older women when taking low doses of hormone therapy.
"Left with the false impression that hormone therapy isn't a safe option, far too many women have suffered in silence thinking their options for symptom relief were limited or non-existent," says Cynthia Stuenkel, MD, a member of The Endocrine Society and an endocrinologist specializing in menopause at the University of California, San Diego. "We know that for some women, hormonal therapy provides the only relief for severe menopausal symptoms. Women deserve some clear answers and helpful tools to engage their doctors in meaningful conversations about the multiple choices available to improve their menopausal symptoms."
When a woman enters menopause, she stops menstruating and her body produces less of the sex hormones estrogen and progesterone. The process of menopause takes years. During that time, women may experience moderate to severe symptoms, including hot flashes, interrupted sleep, vaginal dryness, and other symptoms that affect her quality of life.
The survey found that 72 percent of women currently experiencing symptoms have not received any treatment for them. Other findings include:
Majorities of menopausal women experiencing symptoms have not talked to their primary health care provider or OB/GYN about hormone therapy (62%) or non-hormone options (61%), and half of them have not talked about lifestyle changes;
Nearly half (49%) of menopausal women experiencing symptoms have a negative impression of hormone therapy; and
While the sample sizes of African Americans and Latinas in the survey are small, only 17 percent of African-American respondents say they have talked to their doctors about hormone therapy, compared to 39 percent of white women and 35 percent of Latinas, suggesting that disparities may exist.
"Unfortunately, as in many health care issues, significant disparities exist. Add to that, many primary care doctors don't have enough information about the latest research or what to prescribe," Dr. Stuenkel says. "We want to make health care providers across the nation aware of this tool so that they can facilitate better discussions with their patients."
The "Menopause Map" is an online interactive tool that guides a woman through the different options available to get relief from her symptoms through a series of prompting questions about those symptoms and her personal health history. The Map also has links to questionnaires that help assess current risk for breast cancer, heart disease, and stroke. The tool weighs hormonal and non-hormonal therapies against the risks based on individual symptoms and medical history.
The Map was not designed to be a self-diagnostic tool. It's recommended that women print out their results along with a list of provided questions to discuss the best treatment options for them with their provider. Women should revisit this tool to check their symptoms and have a continuous, informed dialogue with their provider.
The important facts to know about hormone therapy are:
Women 60 years and older should not use menopausal hormone therapy.
Women 50-59 years or younger, with no family or personal history of breast cancer, no history of heart disease or stroke, and with moderate to severe menopausal symptoms are the best candidates for hormone therapy.
If considering hormone therapy, women should talk with their health care provider to determine a plan that is right for them.
In addition, lifestyle approach also helps alleviate symptoms and benefit long-term health.
For those who decide on hormone therapy, this is an ongoing process and might require a period of trial and error to find the right fit for each individual woman.
For those who decide on non-hormonal options, there are several proven therapies available that may help with symptoms. It is important women share information about all medications they are using, including over-the-counter drugs and nutritional supplements, to make sure the choice of therapy doesn't interact with other medications.
###
The Menopause Map can be found at www.hormone.org/MenopauseMap.
About the Survey: The Endocrine Society commissioned Lake Research Partners to conduct a nationally representative survey of 810 women ages 45-60 years old, April 13 -17, 2012. The margin of sampling error is + 4.3 percentage points.
Founded in 1916, The Endocrine Society is the world's oldest, largest, and most active organization devoted to research on hormones and the clinical practice of endocrinology. Today, The Endocrine Society's membership consists of over 15,000 physicians, scientists, educators, nurses and students in more than 100 countries. Society members represent all basic, applied, and clinical interests in endocrinology. The Endocrine Society is based in Chevy Chase, MD. To learn more about the Society, and the field of endocrinology, visit our web site at www.endo-society.org.
The Hormone Health Network works to join Endocrine Society physicians, primary care providers, patients and the public in meaningful, informed discussions about hormones and health. The Network offers patients and their providers free, on-line resources that are based on the Society's most advanced clinical and scientific knowledge of endocrine-related diseases and conditions. Join the Hormone Health Network today by visiting www.hormone.org and subscribing to Hormone Hotline, our monthly e-update on hormones and health.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
First of its kind 'menopause map' helps women navigate treatment Public release date: 1-May-2012 [ | E-mail | Share ]
Nationwide Poll found 7 out of 10 women suffering from menopausal symptoms are not treated; Majority not talking to their doctors about various relief options
May 1, 2012 (Chevy Chase, MD) Women going through menopause now have a first-of-its-kind interactive guide to help them better understand their menu of treatment options, including whether hormone therapy may be right for them. The Endocrine Society and its Hormone Health Network today released the "Menopause Map," an online tool to help women and their doctors discuss which hormonal and non-hormonal treatment options would be most effective and safe to relieve the sometimes debilitating symptoms of menopause. A new accompanying survey found that the majority of women facing challenging symptoms are concerned about hormone treatment and are not discussing it, or other non-hormonal options, with their doctor. The Map was developed by Endocrine Society physician experts who specialize in menopause management.
The tool is based on the latest unbiased research and is intended to jumpstart conversations between women and their doctors about the choices available to them as they approach and experience menopause.
Hormone therapy has been under intense scrutiny since 2002, when a large government study called the Women's Health Initiative (WHI) reported that hormone therapyspecifically the combination of estrogen and progestin togetherincreased the risk for blood clots, stroke, breast cancer and heart attacks. The researchers halted the study and concluded that the risks of hormone therapy outweighed the benefits. Although the study was designed to evaluate the role of hormone therapy in the prevention of diseases related to aging, many women and their doctors also abandoned it as therapy for menopausal symptoms.
Over the past 10 years, additional research has found that the level of risk depends on the individual woman, her health history, age, and the number of years since her menopause began. In general, younger women (under 60) who have recently started menopause are at a lower risk than older women when taking low doses of hormone therapy.
"Left with the false impression that hormone therapy isn't a safe option, far too many women have suffered in silence thinking their options for symptom relief were limited or non-existent," says Cynthia Stuenkel, MD, a member of The Endocrine Society and an endocrinologist specializing in menopause at the University of California, San Diego. "We know that for some women, hormonal therapy provides the only relief for severe menopausal symptoms. Women deserve some clear answers and helpful tools to engage their doctors in meaningful conversations about the multiple choices available to improve their menopausal symptoms."
When a woman enters menopause, she stops menstruating and her body produces less of the sex hormones estrogen and progesterone. The process of menopause takes years. During that time, women may experience moderate to severe symptoms, including hot flashes, interrupted sleep, vaginal dryness, and other symptoms that affect her quality of life.
The survey found that 72 percent of women currently experiencing symptoms have not received any treatment for them. Other findings include:
Majorities of menopausal women experiencing symptoms have not talked to their primary health care provider or OB/GYN about hormone therapy (62%) or non-hormone options (61%), and half of them have not talked about lifestyle changes;
Nearly half (49%) of menopausal women experiencing symptoms have a negative impression of hormone therapy; and
While the sample sizes of African Americans and Latinas in the survey are small, only 17 percent of African-American respondents say they have talked to their doctors about hormone therapy, compared to 39 percent of white women and 35 percent of Latinas, suggesting that disparities may exist.
"Unfortunately, as in many health care issues, significant disparities exist. Add to that, many primary care doctors don't have enough information about the latest research or what to prescribe," Dr. Stuenkel says. "We want to make health care providers across the nation aware of this tool so that they can facilitate better discussions with their patients."
The "Menopause Map" is an online interactive tool that guides a woman through the different options available to get relief from her symptoms through a series of prompting questions about those symptoms and her personal health history. The Map also has links to questionnaires that help assess current risk for breast cancer, heart disease, and stroke. The tool weighs hormonal and non-hormonal therapies against the risks based on individual symptoms and medical history.
The Map was not designed to be a self-diagnostic tool. It's recommended that women print out their results along with a list of provided questions to discuss the best treatment options for them with their provider. Women should revisit this tool to check their symptoms and have a continuous, informed dialogue with their provider.
The important facts to know about hormone therapy are:
Women 60 years and older should not use menopausal hormone therapy.
Women 50-59 years or younger, with no family or personal history of breast cancer, no history of heart disease or stroke, and with moderate to severe menopausal symptoms are the best candidates for hormone therapy.
If considering hormone therapy, women should talk with their health care provider to determine a plan that is right for them.
In addition, lifestyle approach also helps alleviate symptoms and benefit long-term health.
For those who decide on hormone therapy, this is an ongoing process and might require a period of trial and error to find the right fit for each individual woman.
For those who decide on non-hormonal options, there are several proven therapies available that may help with symptoms. It is important women share information about all medications they are using, including over-the-counter drugs and nutritional supplements, to make sure the choice of therapy doesn't interact with other medications.
###
The Menopause Map can be found at www.hormone.org/MenopauseMap.
About the Survey: The Endocrine Society commissioned Lake Research Partners to conduct a nationally representative survey of 810 women ages 45-60 years old, April 13 -17, 2012. The margin of sampling error is + 4.3 percentage points.
Founded in 1916, The Endocrine Society is the world's oldest, largest, and most active organization devoted to research on hormones and the clinical practice of endocrinology. Today, The Endocrine Society's membership consists of over 15,000 physicians, scientists, educators, nurses and students in more than 100 countries. Society members represent all basic, applied, and clinical interests in endocrinology. The Endocrine Society is based in Chevy Chase, MD. To learn more about the Society, and the field of endocrinology, visit our web site at www.endo-society.org.
The Hormone Health Network works to join Endocrine Society physicians, primary care providers, patients and the public in meaningful, informed discussions about hormones and health. The Network offers patients and their providers free, on-line resources that are based on the Society's most advanced clinical and scientific knowledge of endocrine-related diseases and conditions. Join the Hormone Health Network today by visiting www.hormone.org and subscribing to Hormone Hotline, our monthly e-update on hormones and health.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Here's an odd one: average connection speeds around the globe dropped 14 percent to just 2.3 Mbps during the last quarter of 2011. The drop off remains something of a mystery since the data used to calculate that result doesn't include mobile broadband (so its increased adoption can't be dragging down the whole) and Akamai offers no explanation. Still, it's not time to start panicking, just yet. Even though speeds in the US dropped 5.3 percent from the previous quarter, average connection rates are still up significantly over the previous year. Otherwise, things largely stayed the same. Global broadband adoption was steady at 66 percent and the US continued to trail its friends across the Pacific (by a lot) in the race for the fastest Internet connections.
Interestingly, while the number of broadband connections stayed consistent the number of narrowband lines (under 256 Kbps) declined dramatically. Yet, the percentage of the world's population connected to the web managed to increase 2.1 percent quarter over quarter -- and 13 percent for the year. So, while it may seem that the internet had a temporary set back in Q4 of 2011, the long term trends look good. The number of people online is increasing, the average speeds being pulled down by those people is climbing and the number of folks stuck in the dial up era is dropping. To get a copy of the full report hit up the source.
At the end of March, we covered Behance's major site redesign, at which point we learned that the startup was launching over 20K new projects every week, with 1 million projects created to date, and its network had doubled over the last month, with 10 million visits to its network in the last 30 days. Since its founding in 2006 and launch less than a year later, Behance, which, for those unfamiliar, is an online platform on which creative professionals can connect, showcase and discover creative work, has been a bootstrapped enterprise, Behance CEO Scott Belsky tells us. But, no longer. Today, the startup is announcing that it has raised its first round of outside funding, a $6.5 million round, led by Union Square Ventures, with noted investors like Amazon CEO Jeff Bezos (via Bezos Expeditions, his personal investment fund), Path Founder Dave Morin, Yves Behar, Chris Dixon, Dave Tisch, Dave McClure, Alexis Ohanian, and Garrett Camp.
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Public release date: 1-May-2012
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